Gold nanoparticles

Gold nanoparticles (colloidal gold) of different sizes, citrate capped.

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Description

Citrate-capped gold for passive adsorption in aqueous 2 mM sodium citrate. The concentration and surface chemistry of our gold nanoparticles are ideal to be used with the protocol developed by the Mirkin group (Hill et al., 2006) for the high-density conjugation to nucleic acids.

The molar concentration of our gold nanoparticles is determined from TEM and UV-Vis spectra, as described by Haiss et al. (2007). Exact concentrations are reported in the Certificate of Analysis of each batch.

 

Product Data Sheet and Protocol

 

Safety Data Sheet

 

References

  • H. D. Hill, C. A. Mirkin. The bio-barcode assay for the detection of protein and nucleic acid targets using DTT-induced ligand exchange. Nature Protocols, 2006, 1, 324–336. (link)
  • X. Chen, F. Lisi, P. Bakthavathsalam, G. Longatte, S. Hoque, R. D. Tilley, J. J. Gooding. Impact of the Coverage of Aptamers on a Nanoparticle on the Binding Equilibrium and Kinetics between Aptamer and Protein. ACS sensors, 2020, 2021, 6, 2, 538–545. (link)
  • W. Haiss, N. T. K. Thanh, J. Aveyard, D. G. Fernig. Determination of Size and Concentration of Gold Nanoparticles from UV−Vis Spectra. Analytical Chemistry, 2007, 79, 11, 4215–4221. (link)

 

Additional information

Size

10 nm, 30 nm, 50 nm

Amount

15 mL, 0.5 nM, 15 mL, OD = 1